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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NPR2 All Species: 43.03
Human Site: S992 Identified Species: 86.06
UniProt: P20594 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P20594 NP_003986.2 1047 117022 S992 N T A S R M E S N G Q A L K I
Chimpanzee Pan troglodytes XP_001168194 1047 116964 S992 N T A S R M E S N G Q A L K I
Rhesus Macaque Macaca mulatta XP_001085221 1047 116990 S992 N T A S R M E S N G Q A L K I
Dog Lupus familis XP_531993 999 112273 S944 N T A S R M E S N G Q A L K I
Cat Felis silvestris
Mouse Mus musculus Q6VVW5 1047 117039 S992 N T A S R K E S N G Q A L K I
Rat Rattus norvegicus P16067 1047 117109 S992 N T A S R M E S N G Q A L K I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517544 743 84256 D707 T T K D A L D D F G C F Q L A
Chicken Gallus gallus
Frog Xenopus laevis NP_001084176 1082 122776 S1028 N T A S R M E S N G E A L R I
Zebra Danio Brachydanio rerio XP_689479 1088 124806 S1034 N T A S R M E S T G E A L R I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q07553 1163 130896 S1004 N T A S R M E S T G D S M R I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09435 1137 128085 S1029 N T A S R M E S N G K P S L I
Sea Urchin Strong. purpuratus P16065 1125 126238 S1045 N T A S R M E S N G L A L R I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.8 89.1 N.A. 98.5 98.5 N.A. 64.5 N.A. 72.2 58.1 N.A. 32.5 N.A. 28.7 36.2
Protein Similarity: 100 99.9 100 90 N.A. 99.4 99.3 N.A. 67 N.A. 82.9 69.7 N.A. 49 N.A. 46.7 52.2
P-Site Identity: 100 100 100 100 N.A. 93.3 100 N.A. 13.3 N.A. 86.6 80 N.A. 66.6 N.A. 73.3 86.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 100 N.A. 26.6 N.A. 100 93.3 N.A. 86.6 N.A. 80 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 92 0 9 0 0 0 0 0 0 75 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % C
% Asp: 0 0 0 9 0 0 9 9 0 0 9 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 92 0 0 0 17 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 9 0 0 9 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92 % I
% Lys: 0 0 9 0 0 9 0 0 0 0 9 0 0 50 0 % K
% Leu: 0 0 0 0 0 9 0 0 0 0 9 0 75 17 0 % L
% Met: 0 0 0 0 0 84 0 0 0 0 0 0 9 0 0 % M
% Asn: 92 0 0 0 0 0 0 0 75 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 50 0 9 0 0 % Q
% Arg: 0 0 0 0 92 0 0 0 0 0 0 0 0 34 0 % R
% Ser: 0 0 0 92 0 0 0 92 0 0 0 9 9 0 0 % S
% Thr: 9 100 0 0 0 0 0 0 17 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _